Basic Information
ID: ALA4701305
Type: Binding
Description: Inhibition of N-terminal His-GST tagged human PARP14 (1470 to 1801 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 1 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4701305
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.54 | 1.72 | 1.72 |
| 502.57 | 2.56 | 2.56 |
| 518.57 | 1.49 | 1.49 |
| 516.60 | 2.90 | 2.90 |
| 530.63 | 3.20 | 3.20 |
| 545.60 | 1.24 | 1.24 |
| 470.53 | 2.50 | 2.50 |
| 530.59 | 1.87 | 1.87 |
| 472.55 | 2.80 | 2.80 |
| 502.57 | 2.56 | 2.56 |