Basic Information
ID: ALA4701313
Type: Binding
Description: Inhibition of N-terminal GST-tagged human PARP15 (221 to 444 residues) expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4701313
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.53 | 1.04 | 1.04 |
| 530.63 | 3.20 | 3.20 |