Basic Information
ID: ALA4701316
Type: Binding
Description: Inhibition of N-terminal His-GST tagged human PARP14 (1470 to 1801 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4701316
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.53 | 1.04 | 1.04 |
| 472.55 | 2.80 | 2.80 |
| 502.57 | 2.56 | 2.56 |