Basic Information
ID: ALA4701415
Type: Binding
Description: Inhibition of His-tagged human CDK9/cyclin T1 expressed in insect cells using biotin Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins followed by ATP and substrate addition and measured after 25 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Target: CDK9/cyclin T1(ALA2111389)
Document: ALA4699469
Inhibition of His-tagged human CDK9/cyclin T1 expressed in insect cells using biotin Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins followed by ATP and substrate addition and measured after 25 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4701415
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.42 | 2.97 | 2.97 |
| 459.52 | 5.53 | 5.53 |
| 389.41 | 2.22 | 2.22 |
| 459.52 | 5.53 | 5.53 |
| 374.40 | 2.83 | 2.83 |
| 429.45 | 4.76 | 4.76 |
| 402.45 | 3.02 | 3.02 |