Basic Information
ID: ALA4701459
Type: Binding
Description: Inhibition of His-tagged human CDK2 (M1 to L298 residue)/cyclin E1 (M1 to A395 residue) expressed in sf9 insect cells using biotin Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins followed by ATP and substrate addition and measured after 25 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Cyclin-dependent kinase 2/cyclin E1(ALA1907605)
Document: ALA4699469
Inhibition of His-tagged human CDK2 (M1 to L298 residue)/cyclin E1 (M1 to A395 residue) expressed in sf9 insect cells using biotin Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins followed by ATP and substrate addition and measured after 25 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4701459
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.52 | 5.53 | 5.53 |
| 459.52 | 5.53 | 5.53 |
| 429.45 | 4.76 | 4.76 |