Basic Information
ID: ALA4701576
Type: Binding
Description: Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr before CD3 and CD28 stimulation for 20 hrs by AlphaLISA method
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4701576
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 667.62 | 6.47 | 6.47 |
| 667.62 | 6.53 | 6.53 |
| 732.48 | 6.98 | 6.98 |
| 649.63 | 6.33 | 6.33 |
| 678.60 | 6.09 | 6.09 |
| 732.48 | 6.98 | 6.98 |
| 667.62 | 6.47 | 6.47 |
| 688.03 | 6.88 | 6.88 |
| 667.62 | 6.53 | 6.53 |