Basic Information
ID: ALA4701746
Type: Binding
Description: Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase mTOR(ALA2842)
Document: ALA4699485
Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4701746
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.48 | 2.75 | 2.75 |
| 445.48 | 2.75 | 2.75 |
| 427.49 | 1.91 | 1.91 |
| 422.45 | 1.24 | 1.24 |
| 421.46 | 1.85 | 1.85 |