Basic Information
ID: ALA4701849
Type: ADME
Description: Positive allosteric modulation of recombinant human GABA-A alpha1 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4701849
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.41 | 3.39 | 3.39 |
| 418.38 | 3.35 | 3.35 |
| 385.37 | 3.53 | 3.53 |
| 363.42 | 3.33 | 3.33 |
| 347.42 | 3.49 | 3.49 |
| 365.40 | 2.04 | 2.04 |
| 351.37 | 1.73 | 1.73 |
| 350.38 | 2.34 | 2.34 |
| 364.41 | 2.64 | 2.64 |
| 367.38 | 3.08 | 3.08 |