Basic Information
ID: ALA4701891
Type: Binding
Description: Allosteric inhibition of human SHP2 in human KYSE-520 cells assessed as reduction in ERK1/2 phosphorylation by fluorescence based assay
Organism: Homo sapiens
Cell type: KYSE-520 cell line
Activity Charts
Bioactivity
Activity Types for Assay ALA4701891
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.27 | 3.35 | 3.35 |
| 352.27 | 3.35 | 3.35 |
| 353.26 | 2.75 | 2.75 |
| 421.96 | 2.17 | 2.17 |
| 407.93 | 1.78 | 1.78 |
| 421.96 | 2.17 | 2.17 |
| 349.89 | 3.18 | 3.18 |
| 405.96 | 2.94 | 2.94 |
| 398.46 | 3.19 | 3.19 |
| 366.30 | 3.60 | 3.60 |
| 424.50 | 3.72 | 3.72 |
| 384.43 | 2.94 | 2.94 |
| 384.34 | 3.83 | 3.83 |
| 390.94 | 3.36 | 3.36 |
| 366.30 | 3.27 | 3.27 |
| 424.50 | 3.72 | 3.72 |
| 379.92 | 2.41 | 2.41 |
| 398.36 | 4.08 | 4.08 |
| 378.93 | 3.01 | 3.01 |
| 368.27 | 3.48 | 3.48 |