Basic Information
ID: ALA4701908
Type: Functional
Description: Inhibition of SHP2 in mouse xenografted with human KYSE-520 cells assessed as reduction in cellular DUSP6 mRNA levels at 2.5 to 20 mg/kg, po administered as single dose by RT-PCR analysis
Format: BAO_0000218
Organism: Mus musculus
Target: Unchecked(ALA612545)
Document: ALA4699491
Inhibition of SHP2 in mouse xenografted with human KYSE-520 cells assessed as reduction in cellular DUSP6 mRNA levels at 2.5 to 20 mg/kg, po administered as single dose by RT-PCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4701908
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.96 | 2.17 | 2.17 |