ID: ALA4702084
Type: Binding
Description: Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 10 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit)
Organism: Homo sapiens
Cell type: MDA-MB-436
Bioactivity
Activity Types for Assay ALA4702084
Ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
434.47 | 2.35 | 2.35 |
891.01 | 4.86 | 4.86 |
862.96 | 4.08 | 4.08 |
863.00 | 4.83 | 4.83 |
933.09 | 6.03 | 6.03 |
921.04 | 4.48 | 4.48 |
905.04 | 5.25 | 5.25 |
876.99 | 4.47 | 4.47 |
905.04 | 5.25 | 5.25 |
876.99 | 4.47 | 4.47 |
848.93 | 3.69 | 3.69 |
1037.20 | ||
965.09 | 4.50 | 4.50 |
891.01 | 4.81 | 4.81 |