Assay Report Card

Basic Information

ID: ALA4702085

Type: Binding

Description: Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 100 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit)

Organism: Homo sapiens

Cell type: MDA-MB-436

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
434.472.352.35
891.014.864.86
862.964.084.08
863.004.834.83
933.096.036.03
921.044.484.48
905.045.255.25
876.994.474.47
905.045.255.25
876.994.474.47
848.933.693.69
1037.20
965.094.504.50
891.014.814.81