Basic Information
ID: ALA4702086
Type: Binding
Description: Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 1000 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit)
Organism: Homo sapiens
Cell type: MDA-MB-436
Activity Charts
Bioactivity
Activity Types for Assay ALA4702086
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.47 | 2.35 | 2.35 |
| 891.01 | 4.86 | 4.86 |
| 862.96 | 4.08 | 4.08 |
| 863.00 | 4.83 | 4.83 |
| 933.09 | 6.03 | 6.03 |
| 921.04 | 4.48 | 4.48 |
| 905.04 | 5.25 | 5.25 |
| 876.99 | 4.47 | 4.47 |
| 905.04 | 5.25 | 5.25 |
| 876.99 | 4.47 | 4.47 |
| 848.93 | 3.69 | 3.69 |
| 1037.20 | ||
| 965.09 | 4.50 | 4.50 |
| 891.01 | 4.81 | 4.81 |