Assay Report Card

Basic Information

ID: ALA4702125

Type: Binding

Description: Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as induction of PARP1 degradation at 30 nM incubated for 24 hrs in presence of 0.1 to 1 uM CRBN ligand pomalidomide by Western blot analysis

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
876.994.474.47