Basic Information
ID: ALA4702260
Type: Binding
Description: Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by fluorescence assay
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Carboxylesterase 2(ALA3180)
Document: ALA4699508
Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4702260
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.73 | 8.02 | 8.02 |
| 472.71 | 6.06 | 6.06 |
| 424.71 | 8.38 | 8.38 |
| 170.25 | 1.48 | 1.48 |
| 456.67 | 5.74 | 5.74 |
| 496.73 | 7.53 | 7.53 |
| 250.34 | 2.62 | 2.62 |
| 288.34 | 2.07 | 2.07 |
| 234.34 | 3.65 | 3.65 |
| 274.36 | 3.34 | 3.34 |
| 512.78 | 8.00 | 8.00 |
| 184.24 | 1.57 | 1.57 |
| 212.29 | 1.86 | 1.86 |
| 512.78 | 7.86 | 7.86 |