ID: ALA4702271
Type: Binding
Description: Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta production
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PBMC
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA4699510
Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta production: 1
Bioactivity
Activity Types for Assay ALA4702271
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
280.37 | 1.82 | 1.82 |
379.46 | 2.96 | 2.96 |
384.50 | 2.77 | 2.77 |
312.37 | 2.64 | 2.64 |
378.47 | 3.57 | 3.57 |
312.37 | 2.68 | 2.68 |
394.48 | 2.75 | 2.75 |
378.47 | 3.57 | 3.57 |
370.47 | 2.58 | 2.58 |
379.46 | 2.96 | 2.96 |
259.30 | 2.08 | 2.08 |
394.48 | 2.75 | 2.75 |
292.38 | 3.23 | 3.23 |
273.33 | 2.17 | 2.17 |
316.40 | 2.74 | 2.74 |
426.47 | 2.99 | 2.99 |
287.36 | 1.53 | 1.53 |
312.37 | 2.68 | 2.68 |
370.47 | 3.04 | 3.04 |
394.47 | 3.28 | 3.28 |
378.47 | 3.57 | 3.57 |
380.45 | 2.36 | 2.36 |
378.43 | 3.17 | 3.17 |
379.46 | 2.96 | 2.96 |
392.50 | 3.96 | 3.96 |
250.30 | 1.99 | 1.99 |
288.35 | 1.96 | 1.96 |
403.48 | 3.44 | 3.44 |
316.40 | 2.74 | 2.74 |
330.43 | 3.13 | 3.13 |
394.48 | 2.75 | 2.75 |
303.36 | 1.74 | 1.74 |
301.39 | 1.87 | 1.87 |
274.32 | 1.87 | 1.87 |
380.45 | 2.36 | 2.36 |
364.42 | 2.51 | 2.51 |
316.40 | 2.74 | 2.74 |
316.40 | 2.74 | 2.74 |
394.48 | 2.75 | 2.75 |
394.47 | 3.28 | 3.28 |
302.37 | 2.35 | 2.35 |
316.36 | 1.75 | 1.75 |
403.48 | 3.44 | 3.44 |
336.82 | 3.00 | 3.00 |
362.45 | 2.02 | 2.02 |
394.47 | 3.28 | 3.28 |