Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta production

Basic Information

ID: ALA4702271

Type: Binding

Description: Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta production

Format: BAO_0000219

Organism: Homo sapiens

Cell type: PBMC

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document:  ALA4699510

Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta production: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
280.371.821.82
379.462.962.96
384.502.772.77
312.372.642.64
378.473.573.57
312.372.682.68
394.482.752.75
378.473.573.57
370.472.582.58
379.462.962.96
259.302.082.08
394.482.752.75
292.383.233.23
273.332.172.17
316.402.742.74
426.472.992.99
287.361.531.53
312.372.682.68
370.473.043.04
394.473.283.28
378.473.573.57
380.452.362.36
378.433.173.17
379.462.962.96
392.503.963.96
250.301.991.99
288.351.961.96
403.483.443.44
316.402.742.74
330.433.133.13
394.482.752.75
303.361.741.74
301.391.871.87
274.321.871.87
380.452.362.36
364.422.512.51
316.402.742.74
316.402.742.74
394.482.752.75
394.473.283.28
302.372.352.35
316.361.751.75
403.483.443.44
336.823.003.00
362.452.022.02
394.473.283.28