Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluori...

Basic Information

ID: ALA4703666

Type: ADME

Description: Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluorimetric assay

Format: BAO_0000357

Organism: Homo sapiens

Target: Cathepsin L(ALA3837)

Document: ALA4699568

Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluorimetric assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4703666

Total(36)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
337.38	2.16	2.16
307.35	1.67	1.67
269.35	1.57	1.57
303.36	1.76	1.76
401.90	2.35	2.35
341.80	2.32	2.32
396.50	1.84	1.84
362.48	1.65	1.65
299.37	2.00	2.00
333.39	2.20	2.20
297.31	1.26	1.26
379.34	1.42	1.42
337.81	2.42	2.42
297.36	1.90	1.90
309.33	0.46	0.46
349.38	2.48	2.48
295.38	2.10	2.10
271.32	1.37	1.37
367.45	1.70	1.70
313.38	1.73	1.73
335.41	2.45	2.45
307.35	1.67	1.67
353.47	2.81	2.81
359.47	2.03	2.03
341.46	2.67	2.67
346.39	2.15	2.15
393.49	2.23	2.23
427.46	2.89	2.89
333.44	1.50	1.50
341.33	-0.96	-0.96
309.33	0.46	0.46
299.37	2.00	2.00
339.44	2.42	2.42
313.40	1.93	1.93
387.24	1.82	1.82
323.35	1.37	1.37