Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrat...

Basic Information

ID: ALA4703667

Type: Binding

Description: Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluorimetric assay

Format: BAO_0000357

Organism: Trypanosoma cruzi

Target: Cruzipain(ALA3563)

Document: ALA4699568

Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluorimetric assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4703667

Total(36)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
337.38	2.16	2.16
307.35	1.67	1.67
269.35	1.57	1.57
303.36	1.76	1.76
401.90	2.35	2.35
341.80	2.32	2.32
396.50	1.84	1.84
362.48	1.65	1.65
299.37	2.00	2.00
333.39	2.20	2.20
297.31	1.26	1.26
379.34	1.42	1.42
337.81	2.42	2.42
297.36	1.90	1.90
309.33	0.46	0.46
349.38	2.48	2.48
295.38	2.10	2.10
271.32	1.37	1.37
367.45	1.70	1.70
313.38	1.73	1.73
335.41	2.45	2.45
307.35	1.67	1.67
353.47	2.81	2.81
359.47	2.03	2.03
341.46	2.67	2.67
346.39	2.15	2.15
393.49	2.23	2.23
427.46	2.89	2.89
333.44	1.50	1.50
341.33	-0.96	-0.96
309.33	0.46	0.46
299.37	2.00	2.00
339.44	2.42	2.42
313.40	1.93	1.93
387.24	1.82	1.82
323.35	1.37	1.37