Basic Information
ID: ALA4704014
Type: Binding
Description: Inhibition of full-length C-terminal his-tagged human recombinant CHIT1 catalytic domain (1 to 386 residues) expressed in HEK293F cells assessed as reduction in chitinolytic activity using 4-methylumbelliferyl-beta-D-N,N',N"-triacetylchitotrioside as substrate after 60 mins by fluorometric assay
Organism: Homo sapiens
Cell type: HEK293F
Activity Charts
Bioactivity
Activity Types for Assay ALA4704014
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.94 | 3.21 | 3.21 |
| 446.04 | 3.28 | 3.28 |
| 389.94 | 1.87 | 1.87 |
| 376.89 | 1.95 | 1.95 |
| 374.92 | 3.11 | 3.11 |
| 438.96 | 3.52 | 3.52 |
| 390.92 | 2.34 | 2.34 |
| 433.94 | 1.07 | 1.07 |
| 420.95 | 1.97 | 1.97 |
| 433.00 | 3.37 | 3.37 |
| 389.89 | 1.05 | 1.05 |
| 389.89 | 1.05 | 1.05 |
| 434.97 | 2.09 | 2.09 |
| 404.95 | 2.73 | 2.73 |
| 390.92 | 2.34 | 2.34 |
| 406.92 | 1.31 | 1.31 |
| 424.96 | 1.35 | 1.35 |
| 418.97 | 2.98 | 2.98 |