Basic Information
ID: ALA4704262
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activity to IC50 for inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4699588
Selectivity index, ratio of IC50 for inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activity to IC50 for inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4704262
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 640.76 | 4.68 | 4.68 |
| 520.59 | 1.79 | 1.79 |
| 614.74 | 3.08 | 3.08 |
| 547.66 | 2.71 | 2.71 |
| 558.68 | 2.72 | 2.72 |
| 510.51 | 2.24 | 2.24 |
| 541.65 | 1.01 | 1.01 |
| 638.78 | 4.99 | 4.99 |
| 535.65 | 2.64 | 2.64 |
| 569.63 | 2.52 | 2.52 |
| 539.66 | 2.76 | 2.76 |
| 530.62 | 1.98 | 1.98 |
| 532.64 | 2.18 | 2.18 |
| 581.71 | 2.15 | 2.15 |
| 576.69 | 2.94 | 2.94 |
| 562.69 | 3.91 | 3.91 |
| 546.67 | 3.31 | 3.31 |
| 569.66 | 3.11 | 3.11 |
| 568.65 | 3.32 | 3.32 |
| 461.56 | 2.72 | 2.72 |
| 560.70 | 3.70 | 3.70 |
| 547.66 | 2.71 | 2.71 |
| 584.71 | 3.45 | 3.45 |
| 577.68 | 2.34 | 2.34 |
| 570.69 | 3.06 | 3.06 |
| 555.61 | 2.13 | 2.13 |
| 523.59 | 2.29 | 2.29 |
| 556.66 | 1.80 | 1.80 |
| 544.70 | 3.77 | 3.77 |
| 560.69 | 2.96 | 2.96 |
| 537.62 | 1.99 | 1.99 |
| 544.65 | 2.33 | 2.33 |
| 572.71 | 3.11 | 3.11 |
| 548.66 | 3.52 | 3.52 |
| 560.70 | 3.01 | 3.01 |
| 574.72 | 3.40 | 3.40 |
| 525.58 | 2.50 | 2.50 |
| 566.72 | 3.31 | 3.31 |
| 532.64 | 2.92 | 2.92 |
| 539.61 | 2.89 | 2.89 |
| 586.69 | 1.81 | 1.81 |
| 600.71 | 2.69 | 2.69 |