Basic Information
ID: ALA4704485
Type: Binding
Description: Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QXL520 FRET peptide as substrate preincubated for 15 mins followed by substrate addition and measured at 3 mins interval for 60 mins by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Matrix metalloproteinase 12(ALA4393)
Document: ALA4699596
Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QXL520 FRET peptide as substrate preincubated for 15 mins followed by substrate addition and measured at 3 mins interval for 60 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4704485
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.47 | 1.50 | 1.50 |
| 560.65 | 2.06 | 2.06 |
| 578.64 | 2.20 | 2.20 |
| 574.68 | 2.45 | 2.45 |
| 590.68 | 2.07 | 2.07 |
| 595.10 | 2.71 | 2.71 |
| 578.64 | 2.20 | 2.20 |
| 574.68 | 2.37 | 2.37 |
| 628.65 | 3.08 | 3.08 |
| 687.84 | 2.49 | 2.49 |
| 618.69 | 1.98 | 1.98 |
| 574.68 | 2.37 | 2.37 |
| 628.65 | 3.08 | 3.08 |
| 572.66 | 1.84 | 1.84 |
| 595.10 | 2.71 | 2.71 |
| 578.64 | 2.20 | 2.20 |
| 420.44 | 3.15 | 3.15 |
| 614.62 | 2.48 | 2.48 |
| 574.68 | 2.37 | 2.37 |
| 569.66 | 2.57 | 2.57 |
| 576.65 | 1.76 | 1.76 |
| 588.71 | 2.87 | 2.87 |
| 558.68 | 2.86 | 2.86 |
| 717.86 | 2.50 | 2.50 |
| 622.72 | 3.34 | 3.34 |
| 580.69 | 3.24 | 3.24 |
| 658.71 | 1.65 | 1.65 |