Binding affinity to recombinant human 15N-labelled MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus ce...

Basic Information

ID: ALA4704498

Type: Binding

Description: Binding affinity to recombinant human 15N-labelled MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells assessed as ratio of peak intensities of L212 and I220 in bound versus the unbound form at 10 uM by 1D-1H NMR analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Matrix metalloproteinase 12(ALA4393)

Document:  ALA4699596

Binding affinity to recombinant human 15N-labelled MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells assessed as ratio of peak intensities of L212 and I220 in bound versus the unbound form at 10 uM by 1D-1H NMR analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
560.652.062.06
578.642.202.20
574.682.452.45
590.682.072.07
595.102.712.71
578.642.202.20
574.682.372.37
628.653.083.08
618.691.981.98
574.682.372.37
628.653.083.08
572.661.841.84
595.102.712.71
578.642.202.20
614.622.482.48
574.682.372.37
569.662.572.57
576.651.761.76
588.712.872.87
558.682.862.86
622.723.343.34
580.693.243.24
595.102.712.71
658.711.651.65