ID: ALA4704498
Type: Binding
Description: Binding affinity to recombinant human 15N-labelled MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells assessed as ratio of peak intensities of L212 and I220 in bound versus the unbound form at 10 uM by 1D-1H NMR analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Matrix metalloproteinase 12(ALA4393)
Document: ALA4699596
Binding affinity to recombinant human 15N-labelled MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells assessed as ratio of peak intensities of L212 and I220 in bound versus the unbound form at 10 uM by 1D-1H NMR analysis: 1
Bioactivity
Activity Types for Assay ALA4704498
Ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
560.65 | 2.06 | 2.06 |
578.64 | 2.20 | 2.20 |
574.68 | 2.45 | 2.45 |
590.68 | 2.07 | 2.07 |
595.10 | 2.71 | 2.71 |
578.64 | 2.20 | 2.20 |
574.68 | 2.37 | 2.37 |
628.65 | 3.08 | 3.08 |
618.69 | 1.98 | 1.98 |
574.68 | 2.37 | 2.37 |
628.65 | 3.08 | 3.08 |
572.66 | 1.84 | 1.84 |
595.10 | 2.71 | 2.71 |
578.64 | 2.20 | 2.20 |
614.62 | 2.48 | 2.48 |
574.68 | 2.37 | 2.37 |
569.66 | 2.57 | 2.57 |
576.65 | 1.76 | 1.76 |
588.71 | 2.87 | 2.87 |
558.68 | 2.86 | 2.86 |
622.72 | 3.34 | 3.34 |
580.69 | 3.24 | 3.24 |
595.10 | 2.71 | 2.71 |
658.71 | 1.65 | 1.65 |