Basic Information
ID: ALA4704512
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by alamarBlue assay to IC50 for antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation incubated for 7 days by GFP reporter gene assay
Activity Charts
Bioactivity
Activity Types for Assay ALA4704512
Ratio CC50/IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.12 | 3.86 | 3.86 |
| 297.14 | 3.53 | 3.53 |
| 339.18 | 3.91 | 3.91 |
| 426.26 | 4.00 | 4.00 |
| 333.67 | 4.46 | 4.46 |
| 442.37 | 4.97 | 4.97 |
| 408.33 | 4.71 | 4.71 |
| 462.42 | 6.07 | 6.07 |
| 365.26 | 5.31 | 5.31 |
| 430.34 | 5.63 | 5.63 |
| 477.43 | 7.35 | 7.35 |
| 494.42 | 6.01 | 6.01 |
| 381.30 | 5.58 | 5.58 |
| 456.16 | 6.87 | 6.87 |
| 330.82 | 4.65 | 4.65 |
| 379.29 | 5.70 | 5.70 |
| 380.27 | 4.12 | 4.12 |
| 330.82 | 4.65 | 4.65 |
| 437.41 | 7.50 | 7.50 |
| 405.33 | 5.58 | 5.58 |
| 404.25 | 4.66 | 4.66 |
| 421.71 | 6.22 | 6.22 |
| 427.29 | 5.44 | 5.44 |
| 379.29 | 5.23 | 5.23 |
| 467.15 | 5.72 | 5.72 |
| 455.26 | 6.58 | 6.58 |
| 577.55 | 8.73 | 8.73 |
| 387.27 | 5.56 | 5.56 |
| 403.27 | 5.27 | 5.27 |
| 464.39 | 5.45 | 5.45 |
| 353.25 | 5.02 | 5.02 |
| 480.39 | 5.76 | 5.76 |
| 422.70 | 5.61 | 5.61 |
| 344.84 | 4.96 | 4.96 |
| 379.29 | 4.98 | 4.98 |
| 417.29 | 5.57 | 5.57 |
| 349.26 | 5.60 | 5.60 |
| 472.19 | 6.39 | 6.39 |
| 339.22 | 4.77 | 4.77 |
| 473.25 | 6.72 | 6.72 |
| 379.29 | 5.61 | 5.61 |
| 455.26 | 6.58 | 6.58 |
| 523.26 | 7.60 | 7.60 |
| 325.20 | 4.02 | 4.02 |
| 325.20 | 4.38 | 4.38 |
| 365.26 | 5.31 | 5.31 |
| 388.25 | 4.96 | 4.96 |
| 369.25 | 4.13 | 4.13 |
| 466.16 | 6.33 | 6.33 |
| 348.81 | 4.79 | 4.79 |
| 348.81 | 4.79 | 4.79 |
| 340.21 | 3.32 | 3.32 |
| 379.29 | 5.70 | 5.70 |
| 409.36 | 6.72 | 6.72 |
| 405.26 | 5.70 | 5.70 |
| 440.33 | 4.89 | 4.89 |
| 439.70 | 6.36 | 6.36 |
| 339.22 | 4.77 | 4.77 |
| 353.25 | 4.80 | 4.80 |
| 383.28 | 4.52 | 4.52 |
| 355.22 | 3.75 | 3.75 |
| 379.29 | 5.55 | 5.55 |
| 410.30 | 3.70 | 3.70 |
| 351.23 | 4.77 | 4.77 |
| 422.70 | 5.61 | 5.61 |
| 489.71 | 7.24 | 7.24 |
| 413.30 | 3.52 | 3.52 |
| 394.30 | 4.36 | 4.36 |