Assay Report Card

Basic Information

ID: ALA4704550

Type: Binding

Description: Covalent inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells assessed as ratio of Kinact to Ki using Poly (4:1 Glu, Tyr) as substrate preincubated for 2 to 60 mins followed by substrate addition and measured after 1 hr by ADP-glo luminescence assay

Organism: Homo sapiens

Cell type: Sf9

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
640.103.573.57
575.032.902.90
608.583.263.26
642.123.823.82