Basic Information
ID: ALA4704566
Type: Binding
Description: Reversible inhibition of FAK phosphorylation at Tyr397 residue in human U87MG assessed as recovery of FAK autophosphorylation at 0.1 to 5 uM incubated for 48 hrs followed by compound washout with PBS measured by Western blot analysis
Format: BAO_0000221
Organism: Homo sapiens
Cell type: U-87 MG
Target: Focal adhesion kinase 1(ALA2695)
Document: ALA4699600
Reversible inhibition of FAK phosphorylation at Tyr397 residue in human U87MG assessed as recovery of FAK autophosphorylation at 0.1 to 5 uM incubated for 48 hrs followed by compound washout with PBS measured by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4704566
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.95 | 3.82 | 3.82 |
| 640.10 | 3.57 | 3.57 |
| 575.03 | 2.90 | 2.90 |
| 642.12 | 3.82 | 3.82 |