Basic Information
ID: ALA4704588
Type: Binding
Description: Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence based assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4704588
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 175.19 | 1.83 | 1.83 |
| 179.61 | 2.13 | 2.13 |
| 180.60 | 1.52 | 1.52 |
| 162.15 | 1.03 | 1.03 |
| 209.64 | 1.41 | 1.41 |
| 176.17 | 1.75 | 1.75 |
| 230.14 | 2.05 | 2.05 |
| 195.60 | 2.70 | 2.70 |
| 300.79 | 3.40 | 3.40 |
| 196.59 | 1.68 | 1.68 |
| 196.59 | 1.68 | 1.68 |
| 196.59 | 1.68 | 1.68 |
| 195.60 | 1.99 | 1.99 |
| 196.59 | 1.68 | 1.68 |
| 292.34 | 3.56 | 3.56 |
| 176.18 | 1.23 | 1.23 |
| 374.34 | 1.90 | 1.90 |
| 293.67 | 3.27 | 3.27 |
| 175.19 | 1.83 | 1.83 |
| 175.19 | 1.83 | 1.83 |
| 189.22 | 0.97 | 0.97 |
| 202.21 | 1.91 | 1.91 |
| 176.17 | 1.34 | 1.34 |
| 208.65 | 2.45 | 2.45 |
| 223.66 | 1.72 | 1.72 |
| 178.62 | 2.53 | 2.53 |
| 187.16 | 0.90 | 0.90 |
| 207.15 | 0.94 | 0.94 |
| 230.14 | 2.05 | 2.05 |
| 212.66 | 2.15 | 2.15 |
| 212.16 | 1.97 | 1.97 |
| 220.23 | 1.82 | 1.82 |
| 217.23 | 1.02 | 1.02 |
| 176.17 | 1.23 | 1.23 |
| 204.23 | 2.15 | 2.15 |
| 176.17 | 1.34 | 1.34 |
| 280.66 | 3.17 | 3.17 |
| 205.22 | 1.10 | 1.10 |
| 190.20 | 1.59 | 1.59 |
| 180.14 | 1.17 | 1.17 |
| 230.14 | 2.05 | 2.05 |
| 248.59 | 3.41 | 3.41 |
| 180.14 | 1.17 | 1.17 |
| 202.21 | 1.91 | 1.91 |
| 246.27 | 0.92 | 0.92 |
| 212.16 | 1.97 | 1.97 |
| 179.61 | 1.92 | 1.92 |
| 192.17 | 1.04 | 1.04 |
| 244.17 | 2.36 | 2.36 |
| 192.17 | 1.04 | 1.04 |
| 205.22 | 1.10 | 1.10 |
| 221.24 | 1.52 | 1.52 |
| 180.14 | 1.17 | 1.17 |
| 176.17 | 1.23 | 1.23 |
| 190.20 | 1.59 | 1.59 |
| 264.59 | 2.70 | 2.70 |
| 217.23 | 1.02 | 1.02 |
| 270.21 | 2.93 | 2.93 |
| 270.21 | 2.93 | 2.93 |
| 231.04 | 2.34 | 2.34 |
| 272.23 | 3.17 | 3.17 |
| 218.26 | 2.33 | 2.33 |
| 273.21 | 2.11 | 2.11 |