Assay Report Card

Basic Information

ID: ALA4705014

Type: Binding

Description: Competitive inhibition of C-terminal hexahistidine tag in human recombinant PNMT expressed in Escherichia coli assessed as inhibition constant using PEA as substrate in presence of 100 uM AdoMet as co-substrate by Sigma-plot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
384.42-1.44-1.44
176.220.190.19
208.220.600.60
326.38-1.28-1.28
471.590.070.07
527.701.631.63
162.240.660.66
506.030.720.72
485.610.630.63
499.640.850.85
530.610.360.36
485.610.460.46
520.061.111.11
471.590.240.24
485.57-0.41-0.41
544.59-0.11-0.11
520.020.240.24
530.57-0.50-0.50
499.60-0.02-0.02
513.671.241.24
516.58-0.03-0.03