Basic Information
ID: ALA4705574
Type: ADME
Description: Inhibition of human liver microsomes CYP3A at 10 uM using testosterone as substrate in presence of NADPH preincubated for 30 mins followed by substrate addition and measured after 10 mins by LC/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4705574
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.04 | 2.93 | 2.93 |
| 522.58 | 2.42 | 2.42 |
| 524.03 | 2.90 | 2.90 |
| 507.57 | 2.39 | 2.39 |
| 503.61 | 2.56 | 2.56 |
| 518.62 | 2.59 | 2.59 |