Inhibition of human liver microsomes CYP3A at 10 uM using testosterone as substrate in presence of NADPH preincubated for 30 mins followed by substrat...

Basic Information

ID: ALA4705574

Type: ADME

Description: Inhibition of human liver microsomes CYP3A at 10 uM using testosterone as substrate in presence of NADPH preincubated for 30 mins followed by substrate addition and measured after 10 mins by LC/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target: Unchecked(ALA612545)

Document: ALA4699644

Inhibition of human liver microsomes CYP3A at 10 uM using testosterone as substrate in presence of NADPH preincubated for 30 mins followed by substrate addition and measured after 10 mins by LC/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4705574

Inhibition

Total(6)

Parent Molecular Weight	ALogP	Polar Surface Area
539.04	2.93	2.93
522.58	2.42	2.42
524.03	2.90	2.90
507.57	2.39	2.39
503.61	2.56	2.56
518.62	2.59	2.59

Parent Molecular Weight

ALogP

Polar Surface Area

539.04

2.93

522.58

2.42

524.03

2.90

507.57

2.39

503.61

2.56

518.62

2.59

Inhibition of human liver microsomes CYP3A at 10 uM using testosterone as substrate in presence of NADPH preincubated for 30 mins followed by substrat...

Basic Information

Activity Charts

Compound Summary