Basic Information
ID: ALA4705577
Type: Binding
Description: Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential incubated for 5 mins by voltage-clamp assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Oocyte
Target: Neuronal acetylcholine receptor; alpha3/beta2(ALA1907587)
Document: ALA4699645
Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential incubated for 5 mins by voltage-clamp assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4705577
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1679.91 | ||
| 1621.87 | ||
| 1613.85 | ||
| 1653.87 | ||
| 1613.85 | ||
| 1693.98 | ||
| 1678.97 | ||
| 1678.97 | ||
| 1637.83 | ||
| 1680.89 | ||
| 1693.94 | ||
| 1635.90 | ||
| 1651.86 | ||
| 1663.91 | ||
| 1622.86 | ||
| 1653.87 | ||
| 1636.89 |