Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response by measuring recovery ...

Basic Information

ID: ALA4705598

Type: Binding

Description: Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response by measuring recovery of ACh-induced response time at 10 nM with -70 mV holding potential measured after 5 mins voltage-clamp assay

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: Oocyte

Target:  Neuronal acetylcholine receptor; alpha3/beta2(ALA1907587)

Document:  ALA4699645

Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response by measuring recovery of ACh-induced response time at 10 nM with -70 mV holding potential measured after 5 mins voltage-clamp assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1636.89