Basic Information
ID: ALA4705761
Type: Binding
Description: Antagonist activity at human TRPV4 expressed in BHK or HEK MSR2 cells assessed as inhibition of TRPV4 agonist GSK634775 (EC80)-induced response incubated for 10 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4705761
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.33 | 3.60 | 3.60 |
| 397.86 | 2.43 | 2.43 |
| 414.31 | 2.94 | 2.94 |
| 433.29 | 3.11 | 3.11 |
| 377.44 | 2.08 | 2.08 |
| 403.33 | 3.38 | 3.38 |
| 447.32 | 3.45 | 3.45 |
| 432.30 | 3.08 | 3.08 |
| 408.41 | 1.68 | 1.68 |
| 389.30 | 3.07 | 3.07 |
| 432.30 | 3.08 | 3.08 |
| 456.42 | 2.66 | 2.66 |
| 419.33 | 3.08 | 3.08 |
| 432.30 | 3.08 | 3.08 |
| 465.86 | 3.44 | 3.44 |
| 428.34 | 3.25 | 3.25 |
| 439.51 | 3.44 | 3.44 |
| 432.30 | 3.08 | 3.08 |
| 444.34 | 2.95 | 2.95 |
| 388.42 | 1.64 | 1.64 |
| 448.76 | 3.59 | 3.59 |
| 414.31 | 2.94 | 2.94 |
| 407.29 | 3.21 | 3.21 |
| 429.33 | 2.52 | 2.52 |
| 414.31 | 2.94 | 2.94 |
| 397.86 | 2.43 | 2.43 |
| 431.41 | 2.79 | 2.79 |
| 393.44 | 1.78 | 1.78 |
| 397.86 | 2.43 | 2.43 |
| 423.75 | 3.72 | 3.72 |
| 431.41 | 2.79 | 2.79 |
| 446.33 | 3.42 | 3.42 |
| 465.86 | 3.44 | 3.44 |
| 363.41 | 1.77 | 1.77 |
| 447.41 | 2.67 | 2.67 |