Basic Information
ID: ALA4705772
Type: ADME
Description: Time dependent inhibition of recombinant human CYP3A4 expressed in bactosomes at 100 to 300 uM using 7-benzyloxy-4-(trifluoromethyl)-coumarin substrate in presence of NADPH-generating system incubated up to 15 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4705772
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.42 | 2.66 | 2.66 |
| 432.30 | 3.08 | 3.08 |
| 470.45 | 3.05 | 3.05 |
| 429.33 | 2.52 | 2.52 |