Basic Information
ID: ALA4705773
Type: ADME
Description: Time dependent inhibition of CYP3A4 in human liver microsomes pre-incubated for 20 mins before midazolam substrate addition and measured after 10 mins in presence of NADPH
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4705773
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.42 | 2.66 | 2.66 |
| 432.30 | 3.08 | 3.08 |
| 470.45 | 3.05 | 3.05 |
| 429.33 | 2.52 | 2.52 |