Basic Information
ID: ALA4705923
Type: Binding
Description: Inhibition of MALT1 in PMA-stimulated human Jurkat T cells assessed as reduction in IL2 level pretreated for 30 mins followed by PMA-stimulation measured after 5.5 hr by human IL-2 promoter driven bioluminescence assay
Format: BAO_0000221
Organism: Homo sapiens
Cell type: Jurkat
Target: Mucosa-associated lymphoid tissue lymphoma translocation protein 1(ALA3632452)
Document: ALA4699655
Inhibition of MALT1 in PMA-stimulated human Jurkat T cells assessed as reduction in IL2 level pretreated for 30 mins followed by PMA-stimulation measured after 5.5 hr by human IL-2 promoter driven bioluminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4705923
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.28 | 3.78 | 3.78 |
| 414.78 | 4.15 | 4.15 |
| 448.27 | 3.36 | 3.36 |
| 462.30 | 3.41 | 3.41 |
| 474.31 | 3.55 | 3.55 |
| 462.30 | 3.41 | 3.41 |
| 398.78 | 4.56 | 4.56 |
| 370.72 | 3.75 | 3.75 |
| 430.26 | 3.53 | 3.53 |
| 448.27 | 3.36 | 3.36 |
| 434.25 | 2.80 | 2.80 |
| 469.86 | 4.05 | 4.05 |