Basic Information
ID: ALA4706204
Type: ADME
Description: Intrinsic clearance in human liver microsomes at 1 uM measured up to 30 mins in presence of NADPH by UPLC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4706204
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.27 | 3.39 | 3.39 |
| 491.07 | 5.09 | 5.09 |
| 631.63 | 1.65 | 1.65 |
| 755.86 | 4.78 | 4.78 |
| 734.71 | 1.81 | 1.81 |
| 633.65 | 1.90 | 1.90 |
| 757.87 | 4.98 | 4.98 |
| 666.72 | 3.28 | 3.28 |
| 709.71 | 4.42 | 4.42 |
| 617.60 | 1.26 | 1.26 |
| 673.69 | 2.15 | 2.15 |
| 621.59 | 0.50 | 0.50 |
| 635.62 | 0.89 | 0.89 |
| 635.62 | 0.89 | 0.89 |
| 607.56 | -0.16 | -0.16 |
| 605.59 | 1.13 | 1.13 |
| 676.67 | 0.18 | 0.18 |
| 725.71 | 4.09 | 4.09 |
| 715.79 | 3.81 | 3.81 |
| 689.73 | 3.55 | 3.55 |
| 696.58 | 4.37 | 4.37 |
| 713.78 | 3.61 | 3.61 |
| 637.66 | 1.21 | 1.21 |
| 705.78 | 2.47 | 2.47 |
| 685.72 | 3.25 | 3.25 |
| 692.16 | 3.73 | 3.73 |
| 667.66 | 2.48 | 2.48 |
| 687.74 | 3.08 | 3.08 |
| 730.13 | 4.74 | 4.74 |
| 709.71 | 4.42 | 4.42 |
| 651.69 | 1.60 | 1.60 |
| 619.62 | 1.65 | 1.65 |
| 756.84 | 3.11 | 3.11 |
| 681.78 | 4.28 | 4.28 |
| 677.69 | 3.68 | 3.68 |
| 723.75 | 3.31 | 3.31 |
| 647.67 | 2.16 | 2.16 |
| 667.66 | 2.09 | 2.09 |
| 633.65 | 1.90 | 1.90 |
| 710.60 | 4.71 | 4.71 |
| 633.65 | 1.77 | 1.77 |
| 729.82 | 4.20 | 4.20 |
| 605.59 | 1.26 | 1.26 |
| 591.57 | 0.87 | 0.87 |
| 645.66 | 2.04 | 2.04 |
| 673.71 | 2.82 | 2.82 |
| 655.65 | 2.13 | 2.13 |
| 709.71 | 4.42 | 4.42 |
| 675.70 | 3.21 | 3.21 |
| 715.79 | 3.86 | 3.86 |
| 673.71 | 2.69 | 2.69 |
| 619.62 | 1.51 | 1.51 |
| 659.68 | 2.43 | 2.43 |
| 681.69 | 2.35 | 2.35 |
| 777.71 | 5.44 | 5.44 |
| 692.16 | 3.73 | 3.73 |
| 687.74 | 3.08 | 3.08 |
| 765.83 | 2.90 | 2.90 |
| 633.65 | 2.04 | 2.04 |
| 691.77 | 4.56 | 4.56 |
| 577.54 | 0.48 | 0.48 |
| 685.65 | 2.23 | 2.23 |
| 763.68 | 5.10 | 5.10 |
| 743.80 | 3.19 | 3.19 |
| 701.77 | 3.42 | 3.42 |