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Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH

Basic Information

ID: ALA4706260

Type: ADME

Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA4699664

Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4706260

IC50

Total(1)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
354.752.712.71
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