Assay Report Card

Basic Information

ID: ALA4706279

Type: Binding

Description: Inhibition of beta lactamase OXA-48 in Enterobacter cloacae assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis

Organism: Enterobacter cloacae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
265.25-1.53-1.53
269.21-0.49-0.49
377.331.241.24
278.650.190.19
376.27-0.12-0.12
342.230.530.53
312.200.550.55
262.19-0.08-0.08
327.120.790.79
292.680.230.23
344.271.201.20
276.22-0.04-0.04
294.210.250.25
308.240.640.64
244.20-0.38-0.38