Basic Information
ID: ALA4706281
Type: Binding
Description: Inhibition of bacteria beta lactamase OXA-23 assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis
Organism: Bacteria
Activity Charts
Bioactivity
Activity Types for Assay ALA4706281
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 265.25 | -1.53 | -1.53 |
| 269.21 | -0.49 | -0.49 |
| 377.33 | 1.24 | 1.24 |
| 278.65 | 0.19 | 0.19 |
| 376.27 | -0.12 | -0.12 |
| 342.23 | 0.53 | 0.53 |
| 312.20 | 0.55 | 0.55 |
| 262.19 | -0.08 | -0.08 |
| 327.12 | 0.79 | 0.79 |
| 292.68 | 0.23 | 0.23 |
| 344.27 | 1.20 | 1.20 |
| 276.22 | -0.04 | -0.04 |
| 294.21 | 0.25 | 0.25 |
| 308.24 | 0.64 | 0.64 |
| 244.20 | -0.38 | -0.38 |