Basic Information
ID: ALA4706355
Type: Binding
Description: Antagonist activity at CXCR7 (unknown origin) expressed in CHO-K1 cells co-expressing beta-arrestin assessed as reduction in compound-1 induced response pre-incubated for 15 mins before compound-1 addition
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: C-X-C chemokine receptor type 7(ALA2010631)
Document: ALA4699667
Antagonist activity at CXCR7 (unknown origin) expressed in CHO-K1 cells co-expressing beta-arrestin assessed as reduction in compound-1 induced response pre-incubated for 15 mins before compound-1 addition: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4706355
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 310.34 | 2.14 | 2.14 |
| 388.46 | 3.68 | 3.68 |
| 419.47 | 3.77 | 3.77 |
| 389.45 | 4.15 | 4.15 |
| 394.92 | 4.36 | 4.36 |
| 390.43 | 3.54 | 3.54 |
| 361.39 | 3.37 | 3.37 |
| 353.47 | 2.79 | 2.79 |
| 349.34 | 2.36 | 2.36 |
| 433.46 | 3.46 | 3.46 |
| 460.53 | 3.46 | 3.46 |
| 354.45 | 3.26 | 3.26 |
| 425.43 | 4.39 | 4.39 |
| 390.43 | 3.54 | 3.54 |
| 397.43 | 4.01 | 4.01 |
| 419.47 | 3.37 | 3.37 |
| 366.43 | 3.41 | 3.41 |
| 353.41 | 1.63 | 1.63 |
| 479.57 | 6.06 | 6.06 |
| 371.46 | 4.01 | 4.01 |
| 460.53 | 3.46 | 3.46 |
| 366.41 | 2.60 | 2.60 |
| 301.39 | 1.65 | 1.65 |
| 432.36 | 4.63 | 4.63 |
| 352.43 | 3.26 | 3.26 |
| 326.34 | 1.37 | 1.37 |
| 400.47 | 3.95 | 3.95 |
| 432.47 | 3.00 | 3.00 |
| 433.50 | 4.16 | 4.16 |
| 342.48 | 3.56 | 3.56 |
| 355.44 | 1.86 | 1.86 |
| 378.46 | 3.84 | 3.84 |
| 365.38 | 2.46 | 2.46 |
| 313.41 | 1.79 | 1.79 |
| 315.38 | 1.17 | 1.17 |
| 313.41 | 1.79 | 1.79 |
| 371.46 | 4.01 | 4.01 |
| 327.43 | 2.18 | 2.18 |
| 338.40 | 2.92 | 2.92 |
| 284.31 | 1.61 | 1.61 |
| 383.52 | 3.45 | 3.45 |
| 315.42 | 2.04 | 2.04 |
| 420.31 | 3.39 | 3.39 |
| 315.38 | 0.64 | 0.64 |
| 360.47 | 3.70 | 3.70 |
| 421.38 | 4.33 | 4.33 |
| 375.42 | 3.76 | 3.76 |
| 307.30 | 2.10 | 2.10 |
| 324.37 | 2.53 | 2.53 |
| 371.33 | 3.08 | 3.08 |
| 389.45 | 4.15 | 4.15 |
| 405.45 | 3.12 | 3.12 |
| 447.48 | 3.55 | 3.55 |
| 367.50 | 3.10 | 3.10 |
| 389.45 | 3.07 | 3.07 |