Basic Information
ID: ALA4706356
Type: Binding
Description: Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced response pre-incubated for 15 mins before CXCL12-alpha addition and measured after 24 hrs
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA4706356
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 536.62 | 4.73 | 4.73 |
| 536.58 | 3.58 | 3.58 |
| 474.55 | 3.85 | 3.85 |
| 482.49 | 2.27 | 2.27 |
| 388.46 | 3.68 | 3.68 |
| 523.58 | 4.08 | 4.08 |
| 550.65 | 5.07 | 5.07 |
| 419.47 | 3.77 | 3.77 |
| 389.45 | 4.15 | 4.15 |
| 540.55 | 3.14 | 3.14 |
| 390.43 | 3.54 | 3.54 |
| 361.39 | 3.37 | 3.37 |
| 349.34 | 2.36 | 2.36 |
| 433.46 | 3.46 | 3.46 |
| 460.53 | 3.46 | 3.46 |
| 528.54 | 3.00 | 3.00 |
| 508.57 | 5.01 | 5.01 |
| 425.43 | 4.39 | 4.39 |
| 486.56 | 4.00 | 4.00 |
| 390.43 | 3.54 | 3.54 |
| 397.43 | 4.01 | 4.01 |
| 552.62 | 4.22 | 4.22 |
| 419.47 | 3.37 | 3.37 |
| 366.43 | 3.41 | 3.41 |
| 353.41 | 1.63 | 1.63 |
| 479.57 | 6.06 | 6.06 |
| 504.58 | 3.48 | 3.48 |
| 460.53 | 3.46 | 3.46 |
| 537.61 | 4.65 | 4.65 |
| 326.34 | 1.37 | 1.37 |
| 400.47 | 3.95 | 3.95 |
| 537.61 | 4.65 | 4.65 |
| 522.56 | 3.19 | 3.19 |
| 526.54 | 2.28 | 2.28 |
| 536.58 | 3.44 | 3.44 |
| 551.64 | 4.82 | 4.82 |
| 432.47 | 3.00 | 3.00 |
| 433.50 | 4.16 | 4.16 |
| 365.38 | 2.46 | 2.46 |
| 476.52 | 2.48 | 2.48 |
| 537.61 | 4.13 | 4.13 |
| 496.52 | 2.66 | 2.66 |
| 537.61 | 4.65 | 4.65 |
| 522.56 | 3.05 | 3.05 |
| 468.46 | 1.92 | 1.92 |
| 472.54 | 3.61 | 3.61 |
| 536.62 | 5.25 | 5.25 |
| 522.56 | 3.05 | 3.05 |
| 537.61 | 4.65 | 4.65 |
| 446.50 | 3.12 | 3.12 |
| 383.52 | 3.45 | 3.45 |
| 420.31 | 3.39 | 3.39 |
| 522.56 | 3.05 | 3.05 |
| 432.47 | 2.86 | 2.86 |
| 510.55 | 3.04 | 3.04 |
| 375.42 | 3.76 | 3.76 |
| 522.60 | 4.69 | 4.69 |
| 508.53 | 2.80 | 2.80 |
| 307.30 | 2.10 | 2.10 |
| 510.55 | 3.05 | 3.05 |
| 549.62 | 4.57 | 4.57 |
| 558.54 | 3.43 | 3.43 |
| 371.33 | 3.08 | 3.08 |
| 389.45 | 4.15 | 4.15 |
| 405.45 | 3.12 | 3.12 |
| 550.61 | 3.97 | 3.97 |
| 447.48 | 3.55 | 3.55 |
| 389.45 | 3.07 | 3.07 |
| 536.58 | 3.44 | 3.44 |
| 510.50 | 2.18 | 2.18 |