Basic Information
ID: ALA4706363
Type: ADME
Description: Intrinsic clearance in human liver microsomes at 1 uM in presence of NADPH regenerating system incubated up to 45 mins by LC/MS-MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4699667
Intrinsic clearance in human liver microsomes at 1 uM in presence of NADPH regenerating system incubated up to 45 mins by LC/MS-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4706363
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 536.58 | 3.58 | 3.58 |
| 482.49 | 2.27 | 2.27 |
| 540.55 | 3.14 | 3.14 |
| 460.53 | 3.46 | 3.46 |
| 528.54 | 3.00 | 3.00 |
| 552.62 | 4.22 | 4.22 |
| 537.61 | 4.65 | 4.65 |
| 522.56 | 3.19 | 3.19 |
| 526.54 | 2.28 | 2.28 |
| 536.58 | 3.44 | 3.44 |
| 551.64 | 4.82 | 4.82 |
| 537.61 | 4.13 | 4.13 |
| 496.52 | 2.66 | 2.66 |
| 468.46 | 1.92 | 1.92 |
| 536.62 | 5.25 | 5.25 |
| 522.56 | 3.05 | 3.05 |
| 510.55 | 3.04 | 3.04 |
| 522.60 | 4.69 | 4.69 |
| 508.53 | 2.80 | 2.80 |
| 510.55 | 3.05 | 3.05 |
| 549.62 | 4.57 | 4.57 |
| 558.54 | 3.43 | 3.43 |
| 550.61 | 3.97 | 3.97 |
| 536.58 | 3.44 | 3.44 |
| 510.50 | 2.18 | 2.18 |