Basic Information
ID: ALA4706392
Type: Binding
Description: Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12 induced response pre-incubated for 15 mins before CXCL12-alpha addition and measured after 25.5 hrs in presence of 12.3 nM CXCL12 level
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U2OS
Target: C-X-C chemokine receptor type 7(ALA2010631)
Document: ALA4699667
Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12 induced response pre-incubated for 15 mins before CXCL12-alpha addition and measured after 25.5 hrs in presence of 12.3 nM CXCL12 level: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4706392
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.56 | 3.05 | 3.05 |