Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12...

Basic Information

ID: ALA4706395

Type: Binding

Description: Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12 induced response pre-incubated for 15 mins before CXCL12-alpha addition and measured after 25.5 hrs in presence of 333 nM CXCL12 level

Format: BAO_0000219

Organism: Homo sapiens

Cell type: U2OS

Target:  C-X-C chemokine receptor type 7(ALA2010631)

Document:  ALA4699667

Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12 induced response pre-incubated for 15 mins before CXCL12-alpha addition and measured after 25.5 hrs in presence of 333 nM CXCL12 level: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
522.563.053.05