Basic Information
ID: ALA4706872
Type: Functional
Description: Antiplasmodial activity against Plasmodium falciparum 3D7 infected in NSG mouse assessed as blood AUC level require to show 90% reduction in parasitemia administered orally on day 3 post-infection QD for 4 days and measured after 24 hrs post dose by LC-MS/MS analysis
Format: BAO_0000218
Organism: Plasmodium falciparum
Strain: 3D7
Target: Plasmodium falciparum(ALA364)
Document: ALA4706474
Antiplasmodial activity against Plasmodium falciparum 3D7 infected in NSG mouse assessed as blood AUC level require to show 90% reduction in parasitemia administered orally on day 3 post-infection QD for 4 days and measured after 24 hrs post dose by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4706872
AUCED90
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.83 | 4.17 | 4.17 |
| 377.83 | 4.17 | 4.17 |
| 365.33 | 3.40 | 3.40 |