Inhibition of CHK1 (unknown origin) using 5-FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide as substrate incubated for 1 hr in presence of ATP by caliper mic...

Basic Information

ID: ALA4706921

Type: Binding

Description: Inhibition of CHK1 (unknown origin) using 5-FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide as substrate incubated for 1 hr in presence of ATP by caliper microfluidic assay

Format: BAO_0000357

Organism: Homo sapiens

Target: Serine/threonine-protein kinase Chk1(ALA4630)

Document: ALA4706475

Inhibition of CHK1 (unknown origin) using 5-FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide as substrate incubated for 1 hr in presence of ATP by caliper microfluidic assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4706921

IC50

Total(40)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
367.41	1.68	1.68
379.35	1.91	1.91
441.50	2.44	2.44
405.44	2.69	2.69
335.37	0.87	0.87
405.44	2.69	2.69
329.34	1.03	1.03
421.89	3.21	3.21
408.49	2.32	2.32
391.48	2.02	2.02
405.44	2.69	2.69
367.46	1.82	1.82
380.46	1.65	1.65
380.46	1.60	1.60
336.36	0.76	0.76
393.45	1.01	1.01
391.44	2.26	2.26
393.45	2.31	2.31
345.79	1.54	1.54
428.50	3.15	3.15
407.48	2.56	2.56
379.47	2.29	2.29
417.47	2.56	2.56
403.47	3.70	3.70
369.39	0.67	0.67
381.44	2.03	2.03
367.41	1.78	1.78
419.49	1.54	1.54
391.44	1.29	1.29
379.42	1.97	1.97
391.44	1.29	1.29
385.48	3.57	3.57
351.41	1.76	1.76
393.45	1.01	1.01
423.43	2.83	2.83
423.43	2.83	2.83
441.50	2.44	2.44
381.44	2.08	2.08
417.47	2.56	2.56
367.41	1.68	1.68