Intrinsic clearance in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured up to 120 mins by LC-MS/MS analy...

Basic Information

ID: ALA4707024

Type: ADME

Description: Intrinsic clearance in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured up to 120 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target: ADMET(ALA612558)

Document: ALA4706476

Intrinsic clearance in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured up to 120 mins by LC-MS/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4707024

CLH

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
445.52	3.02	3.02
430.51	2.67	2.67
387.44	2.23	2.23

Parent Molecular Weight

ALogP

Polar Surface Area

445.52

3.02

430.51

2.67

387.44

2.23

Intrinsic clearance in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured up to 120 mins by LC-MS/MS analy...

Basic Information

Activity Charts

Compound Summary