Basic Information
ID: ALA4707050
Type: Functional
Description: Ex vivo inhibition of HSP90 in Sprague-Dawley rat assessed as up regulation of HSP70 expression in retina at 20 mg/kg, iv administered for 2 consecutive days and measured 24 hrs post last dose by Western blot analysis
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: Unchecked(ALA612545)
Document: ALA4706476
Ex vivo inhibition of HSP90 in Sprague-Dawley rat assessed as up regulation of HSP70 expression in retina at 20 mg/kg, iv administered for 2 consecutive days and measured 24 hrs post last dose by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4707050
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.51 | 2.67 | 2.67 |