Basic Information
ID: ALA4707176
Type: Binding
Description: Inhibition of PI3K/AKT/mTOR signaling in human HepG2 cells assessed as AKT S473 phosphorylation level at 1 uM incubated for 4 hrs followed by stimulation with 100 ng/ml growth factor IGF1 for 15 mins by Western blot analysis (Rvb = 100 %)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Unchecked(ALA612545)
Document: ALA4706478
Inhibition of PI3K/AKT/mTOR signaling in human HepG2 cells assessed as AKT S473 phosphorylation level at 1 uM incubated for 4 hrs followed by stimulation with 100 ng/ml growth factor IGF1 for 15 mins by Western blot analysis (Rvb = 100 %): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4707176
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.56 | 2.14 | 2.14 |
| 440.51 | 1.76 | 1.76 |
| 454.53 | 2.28 | 2.28 |