Basic Information
ID: ALA4707186
Type: Binding
Description: Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 end residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 measured after 30 mins by fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(ALA2111363)
Document: ALA4706478
Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 end residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 measured after 30 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4707186
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 302.37 | 2.58 | 2.58 |
| 358.49 | 3.24 | 3.24 |
| 508.56 | 2.14 | 2.14 |
| 440.51 | 1.76 | 1.76 |
| 454.53 | 2.28 | 2.28 |
| 440.51 | 1.76 | 1.76 |