Basic Information
ID: ALA4707262
Type: Binding
Description: Inhibition of PI3K/AKT/mTOR signaling in human HuH-7 cells assessed as p70S6K Thr389 phosphorylation level at 1 uM incubated for 4 hrs including last 12 mins stimulation with 20 ng/ml growth factor VEGF by Western blot analysis (Rvb = 100 %)
Organism: Homo sapiens
Cell type: Huh-7
Activity Charts
Bioactivity
Activity Types for Assay ALA4707262
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.83 | 5.55 | 5.55 |
| 513.65 | 2.15 | 2.15 |
| 440.51 | 1.76 | 1.76 |
| 454.53 | 2.28 | 2.28 |
| 440.51 | 1.76 | 1.76 |
| 456.51 | 1.58 | 1.58 |